Psychotropic Drugs And Homicide

After a high-profile homicide case, there is often discussion in the media on whether or not the killing was caused or facilitated by a psychotropic medication. Antidepressants have especially been blamed by non-scientific organizations for a large number of senseless acts of violence, e.g., 13 school shootings in the last decade in the U.S. and Finland [1]. In September 2014, there were more than 139,000 hits from Google for the search terms “antidepressant, homicide”, and more than 1,050,000 hits for the terms “antidepressant, violence”. It is likely that such massive publicity in the lay media has already led a number of patients and physicians to abstain from antidepressant treatment, due to the perceived fear of pharmacologically induced violence.

What is the scientific evidence for an association between psychotropic drugs and homicidal behavior? Most of the available studies are case reports that only suggest a coincidental link between violence or homicide and antidepressants...